Zyban for smoking cessation in a general practice setting: the response to an invitation to make a quit attempt
| Autor: | Elaine C. Johnstone, Robert Walton, Kate Hey, Sarah Roberts, Sarah Welch, Michael F. Murphy, Mark Drury |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty medicine.medical_treatment Prevalence Medicine (miscellaneous) Genetic profile Sex Factors Dopamine Uptake Inhibitors Recurrence medicine Continuous abstinence Humans Treatment Failure Nicotine dependence Bupropion Contraindication Randomized Controlled Trials as Topic Pharmacology business.industry Outcome measures Middle Aged medicine.disease Psychiatry and Mental health Treatment Outcome Retreatment General practice Physical therapy Smoking cessation Female Smoking Cessation Family Practice business Follow-Up Studies |
| DOI: | 10.1080/13556210412331312421 |
| Popis: | The objective of this study was to assess the feasibility and success of Zyban as part of a moderately supported smoking cessation programme within UK general practice. Treatment was offered to 479 moderately dependent smokers (smoking 15 or more cigarettes per day) who had never used Zyban, and who had taken part in a previous NRT trial (the PATCH study). Main outcome measures were point prevalence and continuous abstinence from smoking at 6 and at 12 months. Two hundred and forty were excluded because of medical reasons or prescribing contraindication. Of the remainder (n = 239) only 54 (23%) made an active quit attempt. Thirty percent (16/54) were abstinent at six months, and 22% (12/54) at 12 months (biochemically validated point prevalence rates). Age, socio-economic status, nicotine dependence, and genetic profile appeared to have little impact on success rates, but male quit-attempters were significantly more successful than female (40% vs. 10% at 12 months, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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