Supplemental Figure 3 from Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer

Autor:	David W. Dawson, Ronald M. Evans, Christopher Liddle, Michael Downes, Mara H. Sherman, Claire A. Ostertag-Hill, Anna R. Lay, Kathleen M. Kershaw, Phillip Nguyen, Michael D. Arensman
Rok vydání:	2023
Popis:	Supplemental Figure 3. Calcipotriol reduces VDR message while paradoxically increasing VDR protein levels. (A) VDR expression in AsPC-1 by qPCR after treatments described in Figure 3E. (B) Western blots for VDR or tubulin (loading control) for AsPC-1 lysates at indicated timepoints after calcipotriol treatment. Arrowhead indicates specific band representing VDR protein. qPCR reported as mean {plus minus} SEM. Representative experiments from 2-3 biologic replicates are shown. **P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d63b1d85f186c412e6e26f2e2fe21f https://doi.org/10.1158/1541-7786.22514919.v1 Zobrazit plný text záznamu