Breast involvement in mixed connective tissue disease

Autor: Manju Harshan, Sandor Szilagyi, Ross Varma
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Radiology Case Reports, Vol 14, Iss 4, Pp 430-435 (2019)
Radiology Case Reports
ISSN: 1930-0433
Popis: To date, mammographic involvement in mixed connective tissue disease has not been described in the literature to the authors’ knowledge. In addition, only 2 case reports have described panniculitis in mixed connective tissue disease. We present a patient with mixed connective tissue disease with coarse sheet-like calcifications on mammography bilaterally, which increased over time corresponding to rise in levels of anti-dsDNA. Biopsy showed fat necrosis with calcifications, chronic inflammation and fibrosis, vasculitis, as well as CD3, CD4, and CD8+ T cells and CD20+ B cells. These findings are similar histologically and mammographically to “lupus mastitis.” Keywords: MCTD, Mixed connective tissue disease, Mastitis, Lupus mastitis, MCTD panniculitis, Mammography
Databáze: OpenAIRE