The correlation between the microstructure of meibomian glands and ocular Demodex infestation
| Autor: | Hua Chen, Wanlin Fan, Mingchang Zhang, Sheng-Nan Cheng, Yu-Kan Huang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male China Mite Infestations meibomian glands medicine.medical_specialty Adolescent In vivo confocal microscopy microstructure Observational Study Meibomian gland meibomian glands dysfunction Demodex Gastroenterology Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine parasitic diseases Humans Medicine Eye Infections Parasitic 030212 general & internal medicine Demodex infestation Aged Retrospective Studies Aged 80 and over Chinese population Microscopy Confocal biology business.industry Significant difference Case-control study General Medicine Middle Aged Eye infection biology.organism_classification medicine.anatomical_structure Case-Control Studies correlation 030220 oncology & carcinogenesis Eyelid Diseases Female business Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | Meibomian gland dysfunction (MGD) is a common disease in ophthalmic clinic. This study aimed to explore ocular Demodex infestation on the microstructure changes of the meibomian glands (MGs) in patients with MGD by in vivo confocal microscopy (IVCM). We retrospectively reviewed 103 eyes of 52 patients with MGD and 62 eyes of 31 non-MGD patients. All enrolled patients underwent IVCM examination. The following IVCM parameters were recorded: the MG acinar density (MAD), MG acinar longest diameter (MALD), MG acinar shortest diameter (MASD), MG orifice area (MOA), severity of MG fibrosis (MF), MG acinar irregularity (MAI), meibum secretion reflectivity (MSR), inhomogeneous appearance of walls of acinar units (AWI) and periglandular interstices of acinar units (API), and the number of Demodex. The positive rate of Demodex infestation in MGDs was 89.32%, and statistically higher than control group (controls; P |
| Databáze: | OpenAIRE |
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