Pulmonary AL- amyloidosis masquerading as lung malignancy in an Australian Indigenous patient with Sjogren's syndrome
| Autor: | Madeline Digges, Madeleine Haygarth, Subash S. Heraganahally, Kosala Liyanaarachchi, Akash Kalro, Sumit Mehra |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pathology medicine.medical_specialty Population Case Report 03 medical and health sciences 0302 clinical medicine Lung nodule Eosinophilic AL amyloidosis Medicine education lcsh:RC705-779 education.field_of_study Lung business.industry Amyloidosis Nodule (medicine) lcsh:Diseases of the respiratory system medicine.disease Indigenous medicine.anatomical_structure 030228 respiratory system Sjogren's syndrome 030220 oncology & carcinogenesis Immunohistochemistry medicine.symptom Pulmonary cysts business Wedge resection (lung) |
| Zdroj: | Respiratory Medicine Case Reports Respiratory Medicine Case Reports, Vol 26, Iss, Pp 94-97 (2019) |
| ISSN: | 2213-0071 |
| Popis: | Amyloidosis is a heterogeneous group of disorders characterized by misfolding of extracellular proteins. Pulmonary amyloidosis secondary to Sjogren's syndrome (SS) is rare and to the best our knowledge has not been described in indigenous population. There is also minimal information on its clinical and radiological features. We' describe here 52-year-old Australian Indigenous women with underlying Sjogren's syndrome who was initially suspected to have a metastatic lung cancer with FGD avid lung nodule on PET scan. However, wedge resection of the nodule demonstrated eosinophilic homogenous material that demonstrated apple-green birefringence under polarized light after staining with Congo red with immunohistochemistry pattern in keeping with AL amyloidosis. Keywords: Sjogren's syndrome, Amyloidosis, Lung nodule, Pulmonary cysts, Indigenous |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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