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Background: Previous research has shown that children with Attention Deficit and Hyperactivity Disorder (ADHD) have poor oral health compared to healthy children. Methylphenidate (MP), a widely used stimulant medication for ADHD, was believed to be involved in caries pathophysiology by causing xerostomia. However, a few prospective studies failed to confirm that MP has an independent effect on oral health. Methods: This study is a retrospective cohort of military recruits ages 18-25 who served for 12 to 48 months between 2005 and 2017. The cohort included 6,875 subjects with ADHD who received treatment with MP (Treated), 6,729 subjects with ADHD who had no prescriptions for MP (Untreated) and 200,000 healthy controls. Exposure to MP was measured as total amount of medication in gr, prescribed during the study period. The outcome was normative treatment needs: having at least one recommendation for restorative treatment during the study period. Results: Frequency of recommendation for restorative treatment among the treated, the untreated and the control groups was 24%, 22% and 17%, respectively (p |
