Prevalence and predictors of metabolic syndrome among people living with human immunodeficiency virus (PLWHIV)
| Autor: | Lemessa Dube, Dula Dessalegn Bosho, Mikyas Gashaw Tesfaye, Teshale Ayele Mega, Dawit Abera Adare, Tesfahun C. Eshetie |
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| Přispěvatelé: | Bosho, Dula Dessalegn, Dube, Lemessa, Mega, Teshale Ayele, Adare, Dawit Abera, Tesfaye, Mikyas Gashaw, Eshetie, Tesfahun Chanie |
| Rok vydání: | 2018 |
| Předmět: |
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Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Logistic regression metabolic syndrome 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Environmental health Statistical significance Internal Medicine Medicine 030212 general & internal medicine lcsh:RC620-627 business.industry Research Anthropometry medicine.disease Metabolic syndrome lcsh:Nutritional diseases. Deficiency diseases HIV/AIDS Population study Health education Ethiopia business |
| Zdroj: | Diabetology & Metabolic Syndrome, Vol 10, Iss 1, Pp 1-9 (2018) Diabetology & Metabolic Syndrome |
| ISSN: | 1758-5996 |
| DOI: | 10.1186/s13098-018-0312-y |
| Popis: | Refereed/Peer-reviewed Background: Use of combination antiretroviral therapy (cART) has led to significant reductions in morbidity and mortality. However, there is a growing concern about metabolic syndromes (MS), among patients receiving cART. Despite this fact, there is limited evidence for the prevalence of the MS among HIV-infected persons receiving cART in developing countries, particularly Ethiopia. Objective: To determine the prevalence and predictors of MS among people living with HIV/AIDS in Jimma health centre, Jimma Zone south west Ethiopia. Methods: A cross-sectional study was conducted on people living with HIV/AIDS (PLWHA) in Jimma health centre that fulfilled the inclusion criteria. Data on demographic and anthropometric characteristics were collected using World health organization (WHO) stepwise approach. Fasting blood glucose and lipid profile was measured. The Third Report of National Cholesterol Education Program-adult treatment panel III (NCEP-ATP III)-2001, the International Diabetes Federation (IDF)-2005 and the Joint interim statement-2009 (JIS) criteria were used to define MS. Data were analyzed using statistical software package (SPSS) version 20.0. Logistic regression analysis was done to identify predictors of MS and predictors with p value < 0.05 were used to declare statistical significance. Results: Of 268 HIV-infected participants included in the analysis, 211 (78.7%) were women. The mean age of the participants was 39.32 ± 10.626 years. Using the NCEP-ATP III criteria, the prevalence of MS was found to be 23.5% (63 patients). While it was 20.5% (55 patients) and 27.6% (74 patients) with IDF and JIS criteria respectively. Enrollment in formal education resulted in 75% increment in the odds of MS (AOR = 0.25, 95% CI [0.072–0.879]). The odds of MS in patients with body mass index > 25 kg/m2 was elevated to 13.4 times (AOR = 13.39, 95% CI [3.943–45.525]) and exposure to D-drugs was attributed to 59% increment in the odds of MS (AOR = 1.59, 95% CI [0.58–4.56]), although the finding lacks statistical significance. Conclusions: Metabolic syndromes was relatively common to the study population. Hence, promoting health education and monitoring patient’s clinical and laboratory parameters at every visit and taking appropriate measure is ideal. |
| Databáze: | OpenAIRE |
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