RESPONSE OF CULTURED RABBIT CELLS TO INFECTION WITH THE SHOPE FIBROMA VIRUS I
| Autor: | Harry C. Hinze, Duard L. Walker |
|---|---|
| Rok vydání: | 1964 |
| Předmět: |
Histology
Virus Cultivation Cell Fibroma Biology Kidney Microbiology Cell Line Tissue Culture Techniques Tissue culture Cheek pouch medicine Animals Molecular Biology Cells Cultured Research Articles medicine.disease Virology Molecular biology Fibroma Virus Rabbit medicine.anatomical_structure Rabbits Oncogenic Viruses Oncovirus |
| Zdroj: | Journal of Bacteriology. 88:1185-1194 |
| ISSN: | 1098-5530 0021-9193 |
| DOI: | 10.1128/jb.88.4.1185-1194.1964 |
| Popis: | Hinze, Harry C. (University of Wisconsin, Madison), and Duard L. Walker . Response of cultured rabbit cells to infection with the Shope fibroma virus. I. Proliferation and morphological alteration of the infected cells. J. Bacteriol. 88: 1185–1194. 1964.—Primary and serially cultured rabbit kidney cells were grown under conditions promoting rapid cell multiplication. When such cultures were infected with 5 to 10 plaque-forming units of Shope fibroma virus, cell multiplication was inhibited for a period of 2 to 3 days. After this stationary period, cell multiplication in the infected cultures was resumed at a rate approximating that of the uninfected controls. With the resumption of cell multiplication in the infected cultures, concurrent changes were observed in cell morphology and growth pattern. Cells showing such alterations also possessed the ability to form tumors when inoculated into the hamster cheek pouch. |
| Databáze: | OpenAIRE |
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