Purine transport by Malpighian tubules of pteridine-deficient eye color mutants of Drosophila melanogaster
Autor: | David T. Sullivan, L A Bell, Marie C. Sullivan, D R Paton |
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Rok vydání: | 1979 |
Předmět: |
Malpighian tubule system
Guanine Riboflavin Mutant Guanosine Malpighian Tubules Biology Biochemistry chemistry.chemical_compound Cloaca Guanosine monophosphate Genetics medicine Animals Molecular Biology Ecology Evolution Behavior and Systematics Hypoxanthine Eye Color Biological Transport General Medicine Xanthine Drosophila melanogaster chemistry Xanthines Mutation Pteridine medicine.drug |
Zdroj: | Biochemical Genetics. 17:565-573 |
ISSN: | 1573-4927 0006-2928 |
DOI: | 10.1007/bf00498891 |
Popis: | Uptakes of guanine into Malpighian tubules of wild-type Drosophila and the eye color mutants white (w), brown (bw), and pink-peach (pp) have been compared. Tubules for each of these mutants are unable to concentrate guanine intracellularly. The transport of xanthine and riboflavin is also deficient in w tubules. The transport of guanosine, adenine, hypoxanthine, and guanosine monophosphate is similar in wild-type and white Malpighian tubules. These data and other information about these mutants make it likely that these pteridine-deficient eye color mutants do not produce pigments because of the inability to transport a pteridine precursor. This view supports the hypothesis that mutants which lack both pteridine and ommochromes do so because precursors to both classes of pigments share a common transport system. |
Databáze: | OpenAIRE |
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