Bisamidines of 2,6-diaminoanthraquinone as antiamebic agents
| Autor: | Stanley A. Lang, Yang-I Lin, S. Carvajal, Thomas L. Fields, E. J. Burden, Keith Chadwick Murdock, Paul F. Fabio |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Entamoebiasis
biology Chemistry Entamoeba histolytica Amidines Anthraquinones Amebiasis biology.organism_classification digestive system diseases Rats Microbiology fluids and secretions Cricetinae parasitic diseases Drug Discovery Dysentery Amebic Liver Abscess Amebic Animals Molecular Medicine Female Amebicides |
| Zdroj: | Journal of Medicinal Chemistry. 21:273-276 |
| ISSN: | 1520-4804 0022-2623 |
| Popis: | A series of bisamidines of 2,6-diaminoanthraquinone was synthesized and tested against cecal and hepatic forms of Entamoeba histolytica infections in rats and hamsters, respectively. A number of compounds were found to have good activity against infections in both species. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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