The role of bacterial toxins in sudden infant death syndrome (SIDS)
Autor: | Doris A.C. MacKenzie, Anthony Busuttil, Klára Töro, Ann E. Gordon, C. Caroline Blackwell, Zsuzsanna Csukás, O. M. Al Madani, V. S. James, Péter Sótonyi, O. R. El Ahmer, Donald M. Weir, M. Mogensen-Buchanan |
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Rok vydání: | 2002 |
Předmět: |
Microbiology (medical)
Bacterial Toxins Inflammation Biology medicine.disease_cause Microbiology Sudden death Environmental risk Risk Factors medicine Humans Risk factor Microbial toxins Smoking Infant Newborn Infant General Medicine Bacterial Infections Sudden infant death syndrome Staphylococcal Infections Colonisation Infectious Diseases Staphylococcus aureus Immunology medicine.symptom Sudden Infant Death |
Zdroj: | International journal of medical microbiology : IJMM. 291(6-7) |
ISSN: | 1438-4221 |
Popis: | There is increasing evidence for the involvement of bacterial toxins in some cases of Sudden Infant Death Syndrome (SIDS), particularly the pyrogenic toxins of Staphylococcus aureus . This had led to the hypothesis that some SIDS deaths are due to induction of inflammatory mediators by infectious agents or their products during a period in which the infant is unable to control these normally protective responses. The genetic, developmental and environmental risk factors identified for SIDS are assessed in relation to frequency or density of mucosal colonisation by toxigenic bacteria and their effects on induction and control of inflammatory responses to the toxins. |
Databáze: | OpenAIRE |
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