Low-Dose LEMG-Guided Botulinum Toxin Type A Injection for Intractable Vocal Process Granulomas
| Autor: | Li-Jen Hsin, Yi-Chan Lee, Che-Fang Ho, Li-Ang Lee, Hsueh-Yu Li, Tuan-Jen Fang |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Cricoarytenoid Muscle
medicine.medical_specialty Percutaneous medicine.medical_treatment Vocal Cords Laryngoscopes Botulinum toxin a Lesion 030507 speech-language pathology & audiology 03 medical and health sciences Speech and Hearing 0302 clinical medicine medicine Humans Botulinum Toxins Type A 030223 otorhinolaryngology Adverse effect Saline Granuloma Electromyography business.industry Vocal process LPN and LVN medicine.disease Surgery Otorhinolaryngology Laryngeal Muscles medicine.symptom 0305 other medical science business |
| Zdroj: | Journal of Voice. 36:277-282 |
| ISSN: | 0892-1997 |
| DOI: | 10.1016/j.jvoice.2020.05.018 |
| Popis: | Summary Objective Vocal process granuloma (VPG) has a varied treatment success rate and may frustrate patients and physicians due to poor outcomes. There is still a lack of standard protocols to manage VPG. This study aimed to review the efficiency of a standardized low-dose laryngeal electromyographic (LEMG)-guided botulinum toxin A (BTA) injection in intractable vocal granulomas. Methods Twenty-four patients with intractable VPG were recruited. All patients underwent percutaneous LEMG-guided BTA injection on the thyroarytenoid-lateral cricoarytenoid muscle complex in an office setting. The injecting dose was standardized to 1 U in 0.1 mL normal saline at a time. We evaluated the treatment effect by measuring the lesion size with serial laryngoscope evaluations. Results The postinjection follow-up time varied from 3 to 23 months. Twenty-one patients (87.5%) experienced complete regression of the granuloma over 1–7 months (median 3 months). No major adverse effects were noted during the follow-up period. Conclusion For recalcitrant VPG, LEMG-guided low-dose BTA injection has the potential to be a safe, efficient, and effective treatment. |
| Databáze: | OpenAIRE |
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