Vaginal Adenosarcoma Arising from Endometriosis
| Autor: | William K. Funkhouser, Debra B. Novotny, Wesley C. Fowler, Ana Maria Temple, Patricia L. Judson |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Vaginal Neoplasms medicine.medical_treatment Vaginal Diseases Endometriosis Malignancy Diagnosis Differential Vaginal disease Recurrence medicine Humans Vaginal cancer Pelvic exenteration Adenosarcoma business.industry Obstetrics and Gynecology medicine.disease Cell Transformation Neoplastic medicine.anatomical_structure Oncology Vagina Female business Vaginal Adenosarcoma |
| Zdroj: | Gynecologic Oncology. 76:123-125 |
| ISSN: | 0090-8258 |
| DOI: | 10.1006/gyno.1999.5617 |
| Popis: | Objective. Malignant transformation of endometriosis has been well documented. Endometrioid adenocarcinoma is the most common malignancy to occur in this setting, although other carcinomas and rarely stromal tumors can be seen. We present the first case in the literature of adenosarcoma, a rare mixed mullerian or mesodermal tumor, arising in extrauterine vaginal endometriosis. Case. A 42-year-old woman underwent multiple medical therapies and surgeries for aggressive endometriosis. A pelvic exenteration was abandoned secondary to severe fibrosis, and low-dose radiotherapy was used to control bleeding from vaginal endometriosis. The pathologic diagnosis of recurrent endometriosis was confirmed multiple times over her 4-year course. Excision of a recurrent vaginal mass revealed adenosarcoma with heterologous elements. Conclusion. It is important to biopsy or excise recurrent endometriosis, as malignant transformation can occur, giving rise to epithelial, stromal, or mixed epithelial–mesenchymal tumors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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