Prolonged QT interval and risk of sudden death in South-East Asian men

Autor:	Voranuch Wangsuphachart, M.P. Jones, V. Keane, Ronald G. Munger, R.S. Crow, S. Changbumrung, Ronald J. Prineas
Rok vydání:	1991
Předmět:	Adult Male medicine.medical_specialty Adolescent Minnesota QT interval Sudden death Death Sudden Electrocardiography Risk Factors Seizures Internal medicine Medicine Humans cardiovascular diseases South east asian Refugees business.industry Thiamine Deficiency General Medicine Thailand Long QT Syndrome Laos Cardiology business Sleep
Zdroj:	Lancet (London, England). 338(8762)
ISSN:	0140-6736
Popis:	Sudden death in sleep occurs in substantial numbers among young men in South-East Asia. The frequencies of electrocardiographic abnormalities were measured in groups with varying risks of such sudden death. The mean heart-rate-corrected QT interval (QTc) was significantly (p less than 0.05) greater among 123 Laotian refugees in Thailand at high risk (405 [95% confidence interval 397-413] ms) than in 77 Laotian refugees in the United States at lower risk (364 [359-369] ms) and 199 non-Asian US residents at negligible risk (358 [354-362] ms). Among refugees in Thailand, prolonged QTc interval was associated with poor thiamine status and a history of seizure-like episodes in sleep. Thiamine deficiency may be a cause of prolonged QT interval and sudden death in this region.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919bdc93dc183296dfe19665b108f820 https://pubmed.ncbi.nlm.nih.gov/1677112 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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