Proteomic profiling of human urine using multi-dimensional protein identification technology

Autor:	Henry Brzeski, Michael N. Liebman, Song Yang, Qinhua Cindy Ru, Trevor J. Orchard, Luwang Andy Zhu, Richard A. Katenhusen, Darrell L. Ellsworth, Jordan Silberman
Rok vydání:	2005
Předmět:	Chromatography Proteinuria Proteome Proteomic Profiling Chemistry Organic Chemistry General Medicine Urine Metabolite analysis Proteomics Biochemistry Analytical Chemistry Multi dimensional medicine Humans Protein identification medicine.symptom
Zdroj:	Journal of chromatography. A. 1111(2)
ISSN:	0021-9673
Popis:	Human urine samples are ideal for proteomic profiling and have tremendous potential as sources of biomarkers. Multi-dimensional protein identification technology (MudPIT) is an effective approach to analyzing human urine or other fluids dominated by diverse metabolites. MudPIT analysis was used to identify 87 proteins in just 15 ml of human urine. A high throughput, reproducible, and sensitive technology, MudPIT may soon be used for more proteomic analyses of metabolites.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91986f31bce45a519a42c84de6b08ed3 https://pubmed.ncbi.nlm.nih.gov/16569576 Zobrazit plný text záznamu Full Text from ScienceDirect