Medical Management of Heparin-Induced Thrombocytopenia Causing Acute Adrenal Insufficiency
| Autor: | W. Kalaji, L.N. Gerolemou, Mudita Patel, Jad Sargi, Samridhi Sinha |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
030204 cardiovascular system & hematology Argatroban 03 medical and health sciences 0302 clinical medicine Heparin-induced thrombocytopenia Internal medicine Antithrombotic Adrenal insufficiency Internal Medicine Medicine Thrombus business.industry General Engineering Endocrinology/Diabetes/Metabolism Heparin Hematology medicine.disease Discontinuation Venous thrombosis Cardiology heparin-induced thrombocytopenia business adrenal insufficiency immune mediated phenomenon 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Heparin-induced thrombocytopenia is an immune-mediated reaction to heparin and heparin analogs, which results in an acquired hypercoagulability syndrome resulting in paradoxical arterial and venous thrombosis leading to thrombocytopenia. Organs with high vascularity, such as the adrenal glands, are at an increased risk of injury in heparin-induced thrombocytopenia due to thrombus formation in the adrenal vein causing adrenal insufficiency. The standard of treatment remains discontinuation of heparin and heparin analogs and starting corticosteroids and non-heparin antithrombotic therapy such as argatroban. |
| Databáze: | OpenAIRE |
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