Ultrasonically guided fine-needle aspiration biopsy of portal vein thrombosis: A cytomorphological study of 14 patients

Autor: Juan Madariaga, Moses O. Adeyanju, Andrew Dekker, Gerald D. Dodd
Rok vydání: 1994
Předmět:
Zdroj: Diagnostic Cytopathology. 11:281-285
ISSN: 1097-0339
8755-1039
DOI: 10.1002/dc.2840110317
Popis: Portal vein tumor thrombosis is an important and consistent prognostic indicator in hepatocellular carcinoma. We reviewed 14 cases of ultrasonically guided fine-needle aspiration biopsy (FNAB) of the portal vein. All the patients had clinical evidence of portal vein thrombosis (PVT). Twelve of these patients had a preliminary diagnosis of hepatocellular carcinoma while the remaining two, initially, had a clinical diagnosis of end-stage liver disease. The mean age of the patients was 60 years. An average of 1.7 passes per case was made. No clinical complications were encountered. The cytomorphologic features of the aspirated materials were reviewed. Twelve of the 14 cases (85.7%) were judged neoplastic or thought to have probable neoplastic involvement of the portal vein while two were clearly benign. The cell block was found to be the most useful in diagnosis. We conclude that FNAB of the portal vein is a feasible method in evaluating PVT, especially in patients already known to have hepatocellular carcinoma.
Databáze: OpenAIRE