The HBsAg Prevalence Among Blood Donors From Eastern Mediterranean and Middle Eastern Countries: A Systematic Review and Meta-Analysis
| Autor: | Farid Najafi, Seyed Moayed Alavian, Neda Izadi, Mehran Babanejad |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
HBsAg
Eastern Mediterranean Context (language use) Review Article 030204 cardiovascular system & hematology 03 medical and health sciences Middle East 0302 clinical medicine Environmental health medicine Prevalence 030212 general & internal medicine Hepatitis Hepatology Traditional medicine business.industry Hbsag prevalence Hepatitis B medicine.disease Eastern mediterranean Infectious Diseases Meta-analysis business Meta-Analysis |
| Zdroj: | Hepatitis Monthly |
| ISSN: | 1735-143X |
| Popis: | Context The world health organization (WHO) recommends that all blood donations should be screened for evidence of infections, such as hepatitis B. The present study aimed to determine the prevalence of hepatitis B surface antigen (HBsAg) in blood donors at the eastern Mediterranean region office (EMRO) of the WHO and middle eastern countries. Evidence Acquisition A meta-analysis was carried out based on the results of an electronic literature search of PubMed, Ovid, Scopus, and Google Scholar for articles published from January 1, 2000, to August 31, 2015. In accordance with a significant homogeneity test and a large value of I2, the random effects model was used to aggregate data from the studies and produce the pooled estimates using the “Metan” command. Results We included 66 eligible studies. The pooled prevalence of HBsAg in blood donors of both EMRO and middle eastern (E and M) countries was 2.03% (95% confidence interval [CI]: 1.79 – 2.26). In addition, the prevalence rates in the EMRO countries was 1.99% (95% CI: 1.84 – 2.14) and 1.62% in the Middle Eastern countries (95% CI: 1.36 – 1.88). The prevalence among blood donors with more than one study was 1.58% in Egypt, 0.58% in Iran, 0.67% in Iraq, 2.84% in Pakistan, 3.02% in Saudi Arabia, 1.68% in Turkey, and 5.05% in Yemen. Conclusions Based on the WHO classification of hepatitis B virus (HBV) prevalence, the prevalence of HBsAg in blood donors from E and M countries reached an intermediate level. However, there were low prevalence levels in some E and M countries. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|