Perspectives on interactions between antiepileptic drugs (AEDs) and antimicrobial agents
| Autor: | Joy Desai |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Levetiracetam medicine.medical_treatment Neurocysticercosis Brain Abscess HIV Infections Central nervous system disease Epilepsy Anti-Infective Agents Internal medicine medicine Humans Drug Interactions Clinical significance Aged business.industry Valproic Acid Drug interaction medicine.disease Antimicrobial Piracetam Heart Block Anticonvulsant Neurology Anesthesia Anticonvulsants Female Neurology (clinical) business medicine.drug |
| Zdroj: | Epilepsia. 49:47-49 |
| ISSN: | 1528-1167 0013-9580 |
| DOI: | 10.1111/j.1528-1167.2008.01756.x |
| Popis: | In the treatment of seizures and epilepsy associated with central nervous system (CNS) infections, drug-drug interactions may significantly and unexpectedly impact outcome not only of epilepsy but also of the infectious disorders in both emergent and chronic care situations. A case is described in whom, the administration of the antimicrobial agent, meropenem presumably reduced serum valproate concentrations resulting in impaired seizure control. Other situations are reviewed in which interactions between antiepileptic drugs (AEDs) and antimicrobial agents may be of clinical significance. These include: (1) seizure management in individuals with neurocysticercosis, (2) management of seizures in patients with lobar tuberculomas, (3) management of seizures due to cerebral abscess, and (4) management of seizures in HIV-seropositive individuals. |
| Databáze: | OpenAIRE |
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