Yeast opsonisation in children with chronic diarrhoeal states
| Autor: | John H. Tripp, J F Soothill, Betty A. M. Harvey, D.C.A. Candy, V F Larcher, J T Harries |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Male
medicine.medical_specialty Saccharomyces cerevisiae Gastroenterology Inflammatory bowel disease Coeliac disease Plasma Internal medicine medicine Humans Protracted diarrhoea business.industry digestive oral and skin physiology Immunologic Deficiency Syndromes Infant Chronic diarrhoea Opsonin Proteins medicine.disease Child Preschool Chronic Disease Diarrhea Infantile Pediatrics Perinatology and Child Health Immunology Failure to thrive Immunological abnormality Female Toddler diarrhoea medicine.symptom business Research Article |
| Zdroj: | Archives of Disease in Childhood. 55:189-193 |
| ISSN: | 1468-2044 0003-9888 |
| DOI: | 10.1136/adc.55.3.189 |
| Popis: | Four patients with defective yeast opsonisation and protracted diarrhoea are reported. Plasma infusions improved the opsonising function in all 4 and the diarrhoea in 3. This immunological abnormality was assessed in 100 sequential patients with chronic diarrhoea associated with various gastrointestinal disorders; 52 with protracted diarrhoea and failure to thrive of undetermined cause, 26 with 'toddler diarrhoea', 8 with coeliac disease, 5 with chronic inflammatory bowel disease, and 9 with miscellaneous disorders. 23% of the patients with protracted diarrhoea of undetermined cause had defective opsonisation, a greater proportion (P less than 0.05) than that in 'toddler diarrhoea' or the remaining patients, in whom the frequency (4%) was similar to that (5%) in healthy populations. We suggest that yeast opsonisation be tested in children with protracted diarrhoea, as plasma infusions can be an effective form of treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|