Dietary exposure to environmentally relevant pesticide mixtures impairs swimming performance and lipid homeostatic gene expression in Juvenile Chinook salmon at elevated water temperatures
Autor: | Neil Fuller, Jason T. Magnuson, Kara E. Huff Hartz, Gregory W. Whitledge, Shawn Acuña, Victoria McGruer, Daniel Schlenk, Michael J. Lydy |
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Rok vydání: | 2022 |
Předmět: |
Dichlorodiphenyl Dichloroethylene
Health Toxicology and Mutagenesis Temperature Fishes Water Gene Expression General Medicine Complex Mixtures Toxicology Lipids Pollution Dietary Exposure Salmon ATP Citrate (pro-S)-Lyase Animals Chlorpyrifos Pesticides Fatty Acid Synthases Swimming Liver X Receptors |
Zdroj: | Environmental Pollution. 314:120308 |
ISSN: | 0269-7491 |
Popis: | Aquatic organisms are exposed to complex mixtures of pesticides in the environment, but traditional risk assessment approaches typically only consider individual compounds. In conjunction with exposure to pesticide mixtures, global climate change is anticipated to alter thermal regimes of waterways, leading to potential co-exposure of biota to elevated temperatures and contaminants. Furthermore, most studies utilize aqueous exposures, whereas the dietary route of exposure may be more important for fish owing to the hydrophobicity of many pesticides. Consequently, the current study aimed to determine the effects of elevated temperatures and dietary pesticide mixtures on swimming performance and lipid metabolism of juvenile Chinook salmon, Oncorhynchus tshawytscha. Fish were fed pesticide-dosed pellets at three concentrations and three temperatures (11, 14 and 17 °C) for 14 days and swimming performance (U |
Databáze: | OpenAIRE |
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