Reactivity of Two Selected Antigens of Neisseria gonorrhoeae
| Autor: | John D. Schmale, Dan Danielsson, James D. Thayer, Gilbert Reising |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1969 |
| Předmět: |
Adult
Male Adolescent Virulence Biology medicine.disease_cause Gonococcal infection General Biochemistry Genetics and Molecular Biology Antibodies Microbiology Antigen-Antibody Reactions Gonorrhea Antigen medicine Humans In patient General Pharmacology Toxicology and Pharmaceutics Antigens Soluble antigen General Immunology and Microbiology Complement Fixation Tests General Medicine Middle Aged Virology Neisseria gonorrhoeae Antibody Formation biology.protein Female Clinical Microbiology Virology and Immunology Antibody Gonococcal antibody |
| Popis: | Two antigen preparations, the soluble antigen and a fraction 1 thereof, isolated in the course of a systematic study of the various antigens of the virulent gonococcus, have been investigated for their ability to serve as antigens for the detection of antibody in patients infected with the gonococcus. The soluble antigen was reactive with 88.2% of the sera from infected females, and fraction 1 was reactive with 71.6% of the sera. Of sera from infected males, only 27.6% reacted with the soluble antigen and only 20.4% with fraction 1. Of sera from individuals presumed free of gonococcal infection, approximately 4% reacted with the soluble antigen; none reacted with fraction 1. This study suggests that these antigens might be adaptable to the detection of human gonococcal antibody, especially in the female. |
| Databáze: | OpenAIRE |
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