| Autor: |
Edward E. Graves, Amato J. Giaccia, Kathleen C. Horst, Allison W. Kurian, Melissa J. Jenkins, Anosheh Afghahi, Stavros Melemenidis, Yasaman Ahrari, Meghana A. Golla, Rie von Eyben, Luis A. Soto, Laura L. Bronsart, Marta Vilalta, Todd A. Aguilera, Marjan Rafat |
| Rok vydání: |
2023 |
| DOI: |
10.1158/0008-5472.22418213.v1 |
| Popis: |
Table S1 summarizes the patient radiation and chemotherapy conditions. Figure S1 shows that viable tumor cells are recruited to the MFP following RT. Figure S2 shows that tumor cell recruitment is dose dependent. Figure S3 shows tumor growth curves and lung metastasis after RT. Figure S4 confirms CD4+ and CD8+ T cell depletion in BALB/c mice. Figure S5 presents overall mouse health following MFP RT. Figure S6 illustrates that irradiation of normal cells enhances in vitro cancer cell invasion. Figure S7 evaluates CD8+ T cell infiltration in irradiated normal tissues. Figure S8 shows immune cell infiltration following RT in Nu/Nu mice. Figure S9 shows immune cell infiltration kinetics in BALB/c mice. Figure S10 shows that secreted factors from macrophages influence tumor cell invasion and chemotaxis and that blocking these factors results in a decrease in tumor cell recruitment in vivo. Figure S11 evaluates systemic cytokines following RT. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
