The Infectivity of Pulmonary Tuberculosis in Korean Army Units: Evidence from Outbreak Investigations
| Autor: | Dong Yoon Kang, Mi Hyun Kim, Jaehun Jung, Chang Gyo Yoon, Soo Yon Oh, Hee Jin Kim, Jin Beom Lee, Younsuk Seo |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Asian Continental Ancestry Group
Pulmonary and Respiratory Medicine medicine.medical_specialty Korea Multivariate analysis Tuberculosis Latent tuberculosis business.industry Outbreak Tuberculin bacterial infections and mycoses medicine.disease Tb exposure Disease Outbreaks Military Personnel Infectious Diseases Pulmonary tuberculosis Internal medicine Medicine Original Article Risk factor business |
| Zdroj: | Tuberculosis and Respiratory Diseases |
| ISSN: | 2005-6184 1738-3536 |
| Popis: | Background Tuberculosis (TB) causes substantial health burden to the Korean military. This study aims to assess the impact of infectious TB cases on close and casual contacts in the Korean Army settings based on contact investigation data. Methods Six Army units with infectious TB cases from September 2012 to May 2013 were enrolled in the study. We analyzed the clinical data from close and casual contacts screened using the tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube to identify latent tuberculosis infection (LTBI) cases. For the control group, 286 military conscripts with no reported TB exposure were tested by TST only. Results Of the 667 contacts of index cases, LTBI cases identified were as follows: 21.8% of close contacts of smear-positive cases (71/326), 8.5% of casual contacts of smear-positive cases (26/305), and 2.8% of close contacts of smear-negative cases (1/36). In the control group, 16.8% showed positivity in TST. In a multivariate analysis, having stayed in the same room or next room with TB patients was identified as a risk factor of LTBI. Conclusion Using the data from TB contact investigations in the Korean Army units, we found an overall LTBI rate of 14.7% among the contacts screened. This study demonstrates that contacts living in the same building, especially the same room or next room, with TB patients are at a high risk of acquiring LTBI, serving as additional evidence for defining close and casual contacts of a TB patient with regard to Army barrack settings. |
| Databáze: | OpenAIRE |
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