Lymphangiogenesis and angiogenesis in oral cavity and lower lip squamous cell carcinoma
| Autor: | Shahroo Etemad-Moghadam, Mojgan Alaeddini |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Angiogenesis Lower lip Cell Pathological neovascularization Oral cavity Antibodies Monoclonal Murine-Derived Young Adult 03 medical and health sciences 0302 clinical medicine Squamous cell carcinoma Lymphatic vessel Humans Medicine Basal cell Carcinoma de células escamosas Lymphangiogenesis Aged Lymphatic Vessels Retrospective Studies Aged 80 and over Mouth Neovascularization Pathologic business.industry Boca Linfangiogênese 030206 dentistry Middle Aged Endoglin lcsh:Otorhinolaryngology lcsh:RF1-547 Immunohistochemistry Lábio Lip stomatognathic diseases medicine.anatomical_structure Otorhinolaryngology Neovascularização patológica 030220 oncology & carcinogenesis Lip Neoplasms Microvessels Carcinoma Squamous Cell Female Mouth Neoplasms business |
| Zdroj: | Brazilian Journal of Otorhinolaryngology v.82 n.4 2016 Brazilian Journal of Otorhinolaryngology Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF) instacron:ABORL-CCF Brazilian Journal of Otorhinolaryngology, Vol 82, Iss 4, Pp 385-390 |
| ISSN: | 1808-8694 |
| DOI: | 10.1016/j.bjorl.2015.06.008 |
| Popis: | INTRODUCTION: Tumors of the lip and oral cavity differ in various aspects; therefore a clarification of the distinctions among these sites may help to better understand the biologic behavior of neoplasms occurring in these locations. OBJECTIVE: Considering that angiogenesis and lymphangiogenesis are two major elements that can influence various aspects of tumor biology, we aimed to compare these factors between squamous cell carcinoma of the lower lip and oral cavity. METHODS: A total of 84 primary squamous cell carcinomas including 45 oral and 39 lower lip tumors were selected and immunohistochemically stained with monoclonal antibody against D2-40 and CD105. Mean microvessel density was assessed in tumoral tissue, while lymphatic vessel density was calculated in both neoplastic tissue and invasion front. Data were statistically analyzed using t-test and p-values of |
| Databáze: | OpenAIRE |
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