Genome-wide investigation of genetic changes during modern breeding of Brassica napus
Autor: | Guixin Yan, Jiangwei Qiao, Graham J.W. King, Jingling Meng, Jun Li, Guizhen Gao, Ian Bancroft, Xiaoming Wu, Feng Li, Nian Wang, Biyun Chen, Kun Xu |
---|---|
Rok vydání: | 2014 |
Předmět: |
Linkage disequilibrium
Rapeseed Population Dynamics Context (language use) Breeding Biology Polymorphism Single Nucleotide Genome Chromosomes Plant Linkage Disequilibrium Nucleotide diversity Gene Frequency Genetics Selection Genetic Allele Phylogeny Ecotype Principal Component Analysis Genetic diversity business.industry Brassica napus Genetic Variation Molecular Sequence Annotation General Medicine Biotechnology Evolutionary biology business Agronomy and Crop Science Genome Plant SNP array |
Zdroj: | Theoretical and Applied Genetics. 127:1817-1829 |
ISSN: | 1432-2242 0040-5752 |
Popis: | Considerable genome variation had been incorporated within rapeseed breeding programs over past decades. In past decades, there have been substantial changes in phenotypic properties of rapeseed as a result of extensive breeding effort. Uncovering the underlying patterns of allelic variation in the context of genome organisation would provide knowledge to guide future genetic improvement. We assessed genome-wide genetic changes, including population structure, genetic relatedness, the extent of linkage disequilibrium, nucleotide diversity and genetic differentiation based on F ST outlier detection, for a panel of 472 Brassica napus inbred accessions using a 60 k Brassica Infinium® SNP array. We found genetic diversity varied in different sub-groups. Moreover, the genetic diversity increased from 1950 to 1980 and then remained at a similar level in China and Europe. We also found ~6–10 % genomic regions revealed high F ST values. Some QTLs previously associated with important agronomic traits overlapped with these regions. Overall, the B. napus C genome was found to have more high F ST signals than the A genome, and we concluded that the C genome may contribute more valuable alleles to generate elite traits. The results of this study indicate that considerable genome variation had been incorporated within rapeseed breeding programs over past decades. These results also contribute to understanding the impact of rapeseed improvement on available genome variation and the potential for dissecting complex agronomic traits. |
Databáze: | OpenAIRE |
Externí odkaz: |