Antibacterial constituents from the berries of Piper nigrum
| Autor: | U. Suryanarayana Murthy, K. Hara Kishore, Bhoopathi Praveen, J. Madhusudana Rao, B. China Raju, S. Venkat Reddy, P.V. Srinivas |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Staphylococcus aureus
Pharmaceutical Science Bacillus Bacillus subtilis Enterobacter aerogenes Bacillus sphaericus chemistry.chemical_compound Chromobacterium Drug Discovery Botany Petroleum ether Pharmacology Piper biology Traditional medicine Plant Extracts biology.organism_classification Anti-Bacterial Agents Complementary and alternative medicine chemistry Molecular Medicine Piper nigrum Antibacterial activity Chromobacterium violaceum |
| Zdroj: | Phytomedicine. 11:697-700 |
| ISSN: | 0944-7113 |
| DOI: | 10.1016/j.phymed.2003.04.004 |
| Popis: | Piper nigrum finds an extensive application in antibacterial preparations belonging to Ayurvedic system of medicine. A bioguided extraction and fractionation of the petroleum ether extract of the berries of P. nigrum afforded 2E, 4E, 8Z-N-isobutyleicosatrienamide (1), pellitorine (2), trachyone (3), pergumidiene (4) and isopiperolein B (5). Pergumidiene and trachyone are isolated for the first time from P. nigrum. All the isolated compounds were active against Bacillus subtilis, Bacillus sphaericus, and Staphylococcus aureus amongst Gram + ve bacteria, and Klebsiella aerogenes and Chromobacterium violaceum among Gram -ve bacterial strains. |
| Databáze: | OpenAIRE |
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