Figure S5 from The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State

Autor: Allie H. Grossmann, Sheri L. Holmen, Dean Y. Li, Shannon J. Odelberg, Andrea Bild, David A. Kircher, Coulson P. Rich, Donghan Shin, Tara Mleynek, Roger K. Wolff, Lise K. Sorensen, Jingfu Peng, Aaron Rogers, Lehi Acosta-Alvarez, Samuel W. Brady, Jae Hyuk Yoo
Rok vydání: 2023
DOI: 10.1158/0008-5472.22420620.v1
Popis: Figure S5: ARF6-GTP induces morphologic changes in mouse melanoma cells. Bright field images (100x magnification) of primary mouse melanoma cell lines derived from control BrafCA;Cdkn2af/f (5588) or BrafCA;Cdkn2af/f + Arf6Q67L (6431, 6455) mice. ARF6-GTP induces elongation/spindling of tumor cells relative to the more polygonal-shaped controls. Scale bars = 400um.
Databáze: OpenAIRE