Impact of different storage times at room temperature of unspun citrated blood samples on routine coagulation tests results. Results of a bicenter study and review of the literature
| Autor: | S. Zwahlen, S. Metge, S. Piaulenne, M. Hangard, Pierre Toulon, V. Besson |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Adolescent Clinical Biochemistry Urology 030204 cardiovascular system & hematology Fibrinogen Specimen Handling Young Adult 03 medical and health sciences 0302 clinical medicine medicine Coagulation testing Humans International Normalized Ratio Lead (electronics) Blood Coagulation Aged Prothrombin time biology medicine.diagnostic_test business.industry Biochemistry (medical) Temperature Factor V Reproducibility of Results Hematology General Medicine Middle Aged Surgery Coagulation Blood Preservation Hemostasis biology.protein Female Blood Coagulation Tests business 030215 immunology Partial thromboplastin time medicine.drug |
| Zdroj: | International Journal of Laboratory Hematology. 39:458-468 |
| ISSN: | 1751-5521 |
| DOI: | 10.1111/ijlh.12660 |
| Popis: | SummaryIntroduction A maximum delay between blood collection and coagulation testing of 4 hours is recommended by most guidelines. As information on optimal storage times is limited, we investigated the potential effect of different storage times of unspun tubes, that is, ≤2, 4, 6, and 8 hours, on routine coagulation test results. Methods Four evacuated polymer tubes containing 0.109 mol/L tri-Na citrate were drawn from 144 patients, including 39 patients on vitamin K-antagonists. Except for storage time, all tubes underwent the same preanalytical process. Prothrombin time (PT)/international normalized ratio (INR), activated partial thromboplastin time (aPTT), fibrinogen, factor V (FV), FVIII, and D-dimer were evaluated in two centers using the same technical conditions. Results Analytical comparison of aPTT, fibrinogen, FV, and FVIII results evaluated after prolonged storage times vs a |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |