In Vitro Study on the Effect of a New Bioactive Desensitizer on Dentin Tubule Sealing and Bonding
| Autor: | Laurie Huang, Alireza Sadr, Daniel C.N. Chan, Minh N Luong |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Materials science
Simulated body fluid lcsh:Biotechnology Biomedical Engineering Smear layer microshear bond strength phosphoric acid Article Biomaterials chemistry.chemical_compound stomatognathic system lcsh:TP248.13-248.65 Dentin medicine Composite material Phosphoric acid lcsh:R5-920 Bond strength nanoparticle self-etch stomatognathic diseases medicine.anatomical_structure Dentinal Tubule chemistry SEM Adhesive bioactive desensitizer nanohydroxyapatite Dentin mineralization hypersensitivity lcsh:Medicine (General) |
| Zdroj: | Journal of Functional Biomaterials, Vol 11, Iss 38, p 38 (2020) Journal of Functional Biomaterials Volume 11 Issue 2 |
| ISSN: | 2079-4983 |
| Popis: | Bioactive mineral-based dentin desensitizers that can quickly and effectively seal dentinal tubules and promote dentin mineralization are desired. This in vitro study evaluated a novel nanohydroxyapatite-based desensitizer, Predicta (PBD, Parkell), and its effect on bond strength of dental adhesives. Human dentin discs (2-mm thick) were subjected to 0.5 M EDTA to remove the smear layer and expose tubules, treated with PBD, and processed for surface and cross-sectional SEM examination before and after immersion in simulated body fluid (SBF) for four weeks (ISO 23317-2014). The effects of two dental desensitizers on the microshear bond strength of a universal adhesive and a two-step self-etch system were compared. SEM showed coverage and penetration of nanoparticles in wide tubules on the PBD-treated dentin at the baseline. After four weeks in SBF, untreated dentin showed amorphous mineral deposits while PBD-treated dentin disclosed a highly mineralized structure integrated with dentin. Desensitizers significantly reduced microshear bond strength test (MSBS) of adhesives by 15&ndash 20% on average, depending on the bonding protocol. In conclusion, PBD demonstrated effective immediate tubules sealing capability and promoted mineral crystal growth over dentin and into the tubules during SBF-storage. For bonding to desensitizer-treated dentin, a two-step self-etching adhesive or universal bond with phosphoric acid pretreatment are recommended. |
| Databáze: | OpenAIRE |
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