Cardiac injection of USSC boosts remuscularization of the infarcted heart by shaping the T-cell response

Autor:	Zhaoping, Ding, Kezhe, Tan, Christina, Alter, Sebastian, Temme, Pascal, Bouvain, Christoph, Owenier, Sebastian, Hänsch, Sebastian, Wesselborg, Christoph, Peter, Stefanie, Weidtkamp-Peters, Ulrich, Flögel, Jessica, Schira-Heinen, Kai, Stühler, Julia, Hesse, Gesine, Kögler, Jürgen, Schrader
Rok vydání:	2023
Předmět:	History Polymers and Plastics Business and International Management Cardiology and Cardiovascular Medicine Molecular Biology Industrial and Manufacturing Engineering
Zdroj:	Journal of Molecular and Cellular Cardiology. 175:29-43
ISSN:	0022-2828
Popis:	Regenerating the injured heart remains one of the most vexing challenges in cardiovascular medicine. Cell therapy has shown potential for treatment of myocardial infarction, but low cell retention so far has limited its success. Here we show that intramyocardial injection of highly apoptosis-resistant unrestricted somatic stem cells (USSC) into infarcted rat hearts resulted in an unprecedented thickening of the left ventricular wall with cTnT
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::914b8948ee2727a522e0a12d53228c76 https://doi.org/10.1016/j.yjmcc.2022.11.006 Zobrazit plný text záznamu Full Text from ScienceDirect