The Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting
| Autor: | Benjamin Rohaut, Robert Stevens, Yama Akbari, Daniel Kondziella, Nader Pouratian, Louis Puybasset, Len Polizzotto, Jed A. Hartings, Brian L. Edlow, John Whyte, Nicholas D. Schiff, Amy K. Wagner, Stephan A. Mayer, Geert Meyfroidt, Raimund Helbok, Eric Rosenthal, Paul M. Vespa, Joseph T. Giacino, Theresa Human, Geoffrey S.F. Ling, Soojin Park, J. Claude Hemphill, Molly McNett, Tarek Sharshar, Thomas P. Bleck, Martin M. Monti, Lori Shutter, Mélanie Boly, David K. Menon, Brandon Foreman, Jan Claassen, Daniel F. Hanley, Michael N. Diringer, DaiWai M. Olson, Jose I. Suarez, J. Javier Provencio |
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| Rok vydání: | 2020 |
| Předmět: |
Critical Care
Consciousness DISORDERS media_common.quotation_subject Advisory Committees Clinical Sciences Clinical Neurology TRAUMATIC BRAIN-INJURY Critical Care and Intensive Care Medicine Proof of Concept Study Endotype 03 medical and health sciences 0302 clinical medicine Critical Care Medicine Stakeholder Participation Recovery General & Internal Medicine Humans Medicine In patient 030212 general & internal medicine Coma Implementation Science media_common Clinical Trials as Topic Medical education Science & Technology Neurology & Neurosurgery business.industry Neurological Rehabilitation Neurosciences Neurointensive care Biomarker Decreased consciousness Brain Disorders Neurocritical Care Society Curing Coma Campaign Good Health and Well Being Proceedings Framing (social sciences) Neurology Consciousness Disorders Neurosciences & Neurology Neurology (clinical) business Life Sciences & Biomedicine WITHDRAWAL Biomarkers 030217 neurology & neurosurgery |
| Zdroj: | Neurocritical care, vol 33, iss 1 Provencio, J J, Hemphill, J C, Claassen, J, Edlow, B L, Helbok, R, Vespa, P M, Diringer, M N, Polizzotto, L, Shutter, L, Suarez, J I, Stevens, R D, Hanley, D F, Akbari, Y, Bleck, T P, Boly, M, Foreman, B, Giacino, J T, Hartings, J A, Human, T, Kondziella, D, Ling, G S F, Mayer, S A, McNett, M, Menon, D K, Meyfroidt, G, Monti, M M, Park, S, Pouratian, N, Puybasset, L, Rohaut, B, Rosenthal, E S, Schiff, N D, Sharshar, T, Wagner, A, Whyte, J, Olson, D W M & the Neurocritical Care Society Curing Coma Campaign 2020, ' The Curing Coma Campaign : Framing Initial Scientific Challenges—Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting ', Neurocritical Care, vol. 33, no. 1, pp. 1-12 . https://doi.org/10.1007/s12028-020-01028-9 Neurocritical Care |
| DOI: | 10.1007/s12028-020-01028-9 |
| Popis: | Coma and disordered consciousness are common manifestations of acute neurological conditions and are among the most pervasive and challenging aspects of treatment in neurocritical care. Gaps exist in patient assessment, outcome prognostication, and treatment directed specifically at improving consciousness and cognitive recovery. In 2019, the Neurocritical Care Society (NCS) launched the Curing Coma Campaign in order to address the "grand challenge" of improving the management of patients with coma and decreased consciousness. One of the first steps was to bring together a Scientific Advisory Council including coma scientists, neurointensivists, neurorehabilitationists, and implementation experts in order to address the current scientific landscape and begin to develop a framework on how to move forward. This manuscript describes the proceedings of the first Curing Coma Campaign Scientific Advisory Council meeting which occurred in conjunction with the NCS Annual Meeting in October 2019 in Vancouver. Specifically, three major pillars were identified which should be considered: endotyping of coma and disorders of consciousness, biomarkers, and proof-of-concept clinical trials. Each is summarized with regard to current approach, benefits to the patient, family, and clinicians, and next steps. Integration of these three pillars will be essential to the success of the Curing Coma Campaign as will expanding the "curing coma community" to ensure broad participation of clinicians, scientists, and patient advocates with the goal of identifying and implementing treatments to fundamentally improve the outcome of patients. ispartof: NEUROCRITICAL CARE vol:33 issue:1 pages:1-12 ispartof: location:United States status: published |
| Databáze: | OpenAIRE |
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