The Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting

Autor: Benjamin Rohaut, Robert Stevens, Yama Akbari, Daniel Kondziella, Nader Pouratian, Louis Puybasset, Len Polizzotto, Jed A. Hartings, Brian L. Edlow, John Whyte, Nicholas D. Schiff, Amy K. Wagner, Stephan A. Mayer, Geert Meyfroidt, Raimund Helbok, Eric Rosenthal, Paul M. Vespa, Joseph T. Giacino, Theresa Human, Geoffrey S.F. Ling, Soojin Park, J. Claude Hemphill, Molly McNett, Tarek Sharshar, Thomas P. Bleck, Martin M. Monti, Lori Shutter, Mélanie Boly, David K. Menon, Brandon Foreman, Jan Claassen, Daniel F. Hanley, Michael N. Diringer, DaiWai M. Olson, Jose I. Suarez, J. Javier Provencio
Rok vydání: 2020
Předmět:
Critical Care
Consciousness
DISORDERS
media_common.quotation_subject
Advisory Committees
Clinical Sciences
Clinical Neurology
TRAUMATIC BRAIN-INJURY
Critical Care and Intensive Care Medicine
Proof of Concept Study
Endotype
03 medical and health sciences
0302 clinical medicine
Critical Care Medicine
Stakeholder Participation
Recovery
General & Internal Medicine
Humans
Medicine
In patient
030212 general & internal medicine
Coma
Implementation Science
media_common
Clinical Trials as Topic
Medical education
Science & Technology
Neurology & Neurosurgery
business.industry
Neurological Rehabilitation
Neurosciences
Neurointensive care
Biomarker
Decreased consciousness
Brain Disorders
Neurocritical Care Society Curing Coma Campaign
Good Health and Well Being
Proceedings
Framing (social sciences)
Neurology
Consciousness Disorders
Neurosciences & Neurology
Neurology (clinical)
business
Life Sciences & Biomedicine
WITHDRAWAL
Biomarkers
030217 neurology & neurosurgery
Zdroj: Neurocritical care, vol 33, iss 1
Provencio, J J, Hemphill, J C, Claassen, J, Edlow, B L, Helbok, R, Vespa, P M, Diringer, M N, Polizzotto, L, Shutter, L, Suarez, J I, Stevens, R D, Hanley, D F, Akbari, Y, Bleck, T P, Boly, M, Foreman, B, Giacino, J T, Hartings, J A, Human, T, Kondziella, D, Ling, G S F, Mayer, S A, McNett, M, Menon, D K, Meyfroidt, G, Monti, M M, Park, S, Pouratian, N, Puybasset, L, Rohaut, B, Rosenthal, E S, Schiff, N D, Sharshar, T, Wagner, A, Whyte, J, Olson, D W M & the Neurocritical Care Society Curing Coma Campaign 2020, ' The Curing Coma Campaign : Framing Initial Scientific Challenges—Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting ', Neurocritical Care, vol. 33, no. 1, pp. 1-12 . https://doi.org/10.1007/s12028-020-01028-9
Neurocritical Care
Popis: Coma and disordered consciousness are common manifestations of acute neurological conditions and are among the most pervasive and challenging aspects of treatment in neurocritical care. Gaps exist in patient assessment, outcome prognostication, and treatment directed specifically at improving consciousness and cognitive recovery. In 2019, the Neurocritical Care Society (NCS) launched the Curing Coma Campaign in order to address the "grand challenge" of improving the management of patients with coma and decreased consciousness. One of the first steps was to bring together a Scientific Advisory Council including coma scientists, neurointensivists, neurorehabilitationists, and implementation experts in order to address the current scientific landscape and begin to develop a framework on how to move forward. This manuscript describes the proceedings of the first Curing Coma Campaign Scientific Advisory Council meeting which occurred in conjunction with the NCS Annual Meeting in October 2019 in Vancouver. Specifically, three major pillars were identified which should be considered: endotyping of coma and disorders of consciousness, biomarkers, and proof-of-concept clinical trials. Each is summarized with regard to current approach, benefits to the patient, family, and clinicians, and next steps. Integration of these three pillars will be essential to the success of the Curing Coma Campaign as will expanding the "curing coma community" to ensure broad participation of clinicians, scientists, and patient advocates with the goal of identifying and implementing treatments to fundamentally improve the outcome of patients. ispartof: NEUROCRITICAL CARE vol:33 issue:1 pages:1-12 ispartof: location:United States status: published
Databáze: OpenAIRE