Enemy Beyond the Wall: Clinicopathological Features of Intrathyroidal Papillary Thyroid Carcinoma (T1-T3a) That Metastasize to Lymph Nodes Without Extrathyroidal Extension
Autor: | Reyhan Ersoy, Husniye Baser, Abbas Ali Tam, Mehmet Kilic, Bekir Cakir, Oya Topaloglu, Aysegul Aksoy Altinboga, Nurcan Ince, Afra Alkan, Didem Ozdemir |
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Rok vydání: | 2021 |
Předmět: |
Male
0301 basic medicine Cancer Research Pathology medicine.medical_specialty endocrine system diseases Lymph node metastasis Vascular invasion Thyroid carcinoma 03 medical and health sciences 0302 clinical medicine Humans Medicine Neoplasm Metastasis business.industry Incidence General Medicine 030104 developmental biology Oncology Thyroid Cancer Papillary Lymphatic Metastasis 030220 oncology & carcinogenesis Clinicopathological features Female Lymph business |
Zdroj: | Cancer Investigation. 39:401-408 |
ISSN: | 1532-4192 0735-7907 |
DOI: | 10.1080/07357907.2021.1897833 |
Popis: | The aim of this study was to determine the clinicopathological features of papillary thyroid carcinomas (PTC) without extrathyroidal extension (ETE) and with lymph node metastasis (LNM). PTC1 cm increased the risk of LNM by 2.161 times compared to papillary thyroid microcarcinoma. The risk increased by 3.774 times in males and 1.553 times in the presence of multifocality. Presence of vascular invasion (VI) increased the risk of LNM by 3.093 times in patients without capsular invasion (CI). Clinicians should be careful about possible LNM in patients with large primary tumor diameter, multifocal tumors, CI and VI. |
Databáze: | OpenAIRE |
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