How Does Sodium Lauryl Sulfate Alter the Skin Barrier Function in Man? A Multiparametric Approach
| Autor: | Didier Saint-Leger, J. L. Leveque, J. de Rigal, D. Billy |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Physiology Sodium chemistry.chemical_element Dermatology chemistry.chemical_compound In vivo Sodium sulfate Stratum corneum medicine Humans Sodium dodecyl sulfate Lipid bilayer Skin Ultrasonography Pharmacology Transepidermal water loss Chromatography integumentary system Chemistry Sodium Dodecyl Sulfate General Medicine Lipids medicine.anatomical_structure Toxicity Biophysics Female |
| Zdroj: | Skin Pharmacology and Physiology. 6:111-115 |
| ISSN: | 1660-5535 1660-5527 |
| DOI: | 10.1159/000211095 |
| Popis: | The effects of topically applied sodium lauryl sulfate were studied in vivo, in man, through noninvasive methods and compared with those obtained in vitro, using human stratum corneum as a model. The results show that the very marked increase of transepidermal water loss obtained in vivo cannot be related to any removal of epidermal lipids. The most likely explanation of our findings lies in the hyperhydration of stratum corneum consecutive to the inflammation process and a possible disorganization of the lipid bilayers. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|