Plasma transport of 99mTc-p-butyl-IDA
| Autor: | Eric Gremillet, Michelle Voutay, Adib Kassir, Marielle Decousus, André Champailler, Jean-Claude Healy |
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| Rok vydání: | 1985 |
| Předmět: |
Chromatography
biology Imino Acids Serum albumin Albumin Technetium Biological Transport General Medicine Plasma protein binding Metabolism Organotechnetium Compounds Transport protein Electrophoresis chemistry.chemical_compound chemistry Blood plasma biology.protein Humans Radiology Nuclear Medicine and imaging Trichloroacetic acid Carrier Proteins Serum Albumin Protein Binding |
| Zdroj: | European journal of nuclear medicine. 10(9-10) |
| ISSN: | 0340-6997 |
| Popis: | Plasma transport of 99mTc-p-butyl-IDA was measured by four in vitro methods: trichloroacetic acid precipitation, electrophoresis, HPLC, and Scatchard binding isotherm. The data are in accord with protein transport, the main carrier being albumin with two categories of sites. This work suggests that after IV injection of 99mTc-p-butyl-IDA in humans plasma protein binding is one of the limiting factors for the hepatic deposition of the radiopharmacentical. |
| Databáze: | OpenAIRE |
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