Is atrial fibrillation a risk factor for worse outcomes in severe COVID-19 patients: a single center retrospective cohort
Autor: | Fawaz Bardooli, Shereen AlShaikh, Abdulkarim Abdulrahman, Safraz Nawaz, Abdulrahman Almadani, Tajammul Hussain |
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Rok vydání: | 2021 |
Předmět: |
Corona virus
medicine.medical_specialty Critical Care business.industry Medical record COVID-19 Atrial fibrillation Retrospective cohort study Odds ratio arrythmia medicine.disease Logistic regression Sars-CoV2 Internal medicine ICU Bahrain Cohort medicine Original Article Sinus rhythm Risk factor Cardiology and Cardiovascular Medicine business atrial arrythmia |
Zdroj: | Journal of the Saudi Heart Association |
ISSN: | 2212-5043 |
Popis: | Introduction New onset atrial fibrillation leads to worse outcomes in patients with sepsis. The association between new onset atrial fibrillation (AF) in COVID19 patients with COVID19 outcomes are lacking. This study aims to determine whether new onset atrial fibrillation in COVID19 patients admitted in the ICU is a risk factor for death or requirement of mechanical ventilation (MV). Methods This is a retrospective study conducted in a cohort of COVID-19 patients admitted to Bahrain Defence Force COVID19 Field ICU between April 2020 to November 2020. Data were extracted from the electronic medical records. The patients who developed new onset AF during admission were compared to patients who remained in sinus rhythm. Multivariate logistic regression models were used to control for confounders and estimate the effect of AF on the outcomes of these patients. Results Our study included a total of 492 patients out of which 30 were diagnosed with new onset AF. In the AF group, the primary outcome occurred in 66.7% of patients (n = 20). In the control group, 17.1% (n = 79) developed the primary outcome. Upon adjusting for the confounders in the multivariate regression model, AF had an odds ratio of 3.96 (95% CI: 1.05-14.98; p = 0.042) for the primary outcome. Conclusion Our results indicate that new onset AF is a risk factor for worse outcomes in patients admitted with COVID19 in the ICU. |
Databáze: | OpenAIRE |
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