Role of antioxidants and a nutrient rich diet in Alzheimer's disease
| Autor: | Sandeep Singh, George Perry, Gerald Veurink |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
antioxidant
Antioxidant medicine.medical_treatment Intracellular pH Immunology Review Review Article Biology Pharmacology medicine.disease_cause Neuroprotection Antioxidants General Biochemistry Genetics and Molecular Biology Nutrient density 03 medical and health sciences 0302 clinical medicine Nutraceutical Alzheimer Disease medicine Extracellular Humans lcsh:QH301-705.5 030304 developmental biology 0303 health sciences nutrient General Neuroscience Drug Synergism Metabolic acidosis Alzheimer's disease medicine.disease Diet Oxidative Stress lcsh:Biology (General) Dietary Supplements neuroprotection nutraceutical 030217 neurology & neurosurgery Oxidative stress |
| Zdroj: | Open Biology Open Biology, Vol 10, Iss 6 (2020) |
| ISSN: | 2046-2441 |
| DOI: | 10.1098/rsob.200084 |
| Popis: | The joint attack on the body by metabolic acidosis and oxidative stress suggests that treatment in degenerative diseases, including Alzheimer's disease (AD), may require a normalizing of extracellular and intracellular pH with simultaneous supplementation of an antioxidant combination cocktail at a sufficiently high dose. Evidence is also accumulating that combinations of antioxidants may be more effective, taking advantage of synergistic effects of appropriate antioxidants as well as a nutrient-rich diet to prevent and reverse AD. This review focuses on nutritional, nutraceutical and antioxidant treatments of AD, although they can also be used in other chronic degenerative and neurodegenerative diseases. |
| Databáze: | OpenAIRE |
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