A Radical Procedure for the Anti-Markovnikov Hydroazidation of Alkenes

Autor:	Ajoy Kapat, Philippe Renaud, Florian Montermini, Andreas König
Rok vydání:	2011
Předmět:	Azides Radical procedure Markovnikov's rule Regioselectivity Stereoisomerism General Chemistry Alkenes Biochemistry Catalysis chemistry.chemical_compound Hydroboration Colloid and Surface Chemistry chemistry Organic chemistry Radical initiator Azide Boranes Catecholborane
Zdroj:	Journal of the American Chemical Society. 133:13890-13893
ISSN:	1520-5126 0002-7863
DOI:	10.1021/ja2054989
Popis:	A one-pot procedure for the efficient hydroazidation of alkenes involving hydroboration with catecholborane followed by reaction with benzenesulfonyl azide in the presence of a radical initiator is described. The regioselectivity is controlled by the hydroboration step and corresponds in most cases to an anti-Markovnikov regioselectivity. This procedure is applicable to a wide range of alkenes and gives excellent results with 1,2-disubstituted and trisubstituted alkenes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9118e3699a1ca1adb2b20264b82b7310 https://doi.org/10.1021/ja2054989 Zobrazit plný text záznamu