Oxidative Damage and Reproductive Toxicity Associated with Antouka Super® in Male Japanese Quail (Coturnix coturnix japonica): The Protective Effects of Hydroethanolic Leaves Extract of Persea americana
Autor: | Nguemmogne Tamdem Ghislaine, Mutwedu Valence, Ngouateu Kenfack Omer Bebe, Ngoumtsop Victor Herman, Ngoula Ferdinand, Kenfack Augustave, Manjeli Yacouba, Tchoffo Herve, Deutcheu Nienga Sorelle, Azafack Kana Dorice |
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Rok vydání: | 2017 |
Předmět: |
reproductive toxicity
Persea Traditional medicine Persea Americana (HEPA) oxidative damage Biology hydroethanolic leaves extract biology.organism_classification General Biochemistry Genetics and Molecular Biology Japonica Quail Oxidative damage Antouka Super® (AS) Japanese quail biology.animal Botany Coturnix coturnix General Agricultural and Biological Sciences Reproductive toxicity |
Popis: | The present study was undertaken to evaluate the protective role of hydroethanolic leaves extract of The present study was undertaken to evaluate the protective role of Hydroethanolic leaves Persea americana (HEPA) against reproductive toxicity induced by Antouka Super® (AS) in male Japanese quail. The study was carried out in the Teaching and Research Farm of University of Dschang between February and May 2016. Forty (40) immature male Japanese quails (28 days old), were divided into five groups of 8 birds each and subjected to the following treatments: Group 1, birds receiving 10 ml/kg b.w of distilled water (negative control group (CO-); Group 2, birds receiving 75 mg of AS/kg (positive control group (CO+). while groups 3, 4 and 5 were administered 50, 100 and 200 mg/ kg b.w of HEPA respectively together with AS at 75 mg/kg. All the test solutions were orally administered once a day for 60 days using an endogastric canule. Dissection of the vas deferent was performed to obtain spermatozoa. The protective effects of HEPA on the organ weights, serum hormones, oxidative stress biomarkers, sperm characteristics and histology changes in the testes were evaluated. Results revealed that exposure to AS significantly (p |
Databáze: | OpenAIRE |
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