Large outbreak of Salmonella enterica serotype paratyphi B infection caused by a goats' milk cheese, France, 1993: a case finding and epidemiological study
| Autor: | Isabelle Rebière, Elisabeth Benz-Lemoine, Francine Grimont, Philippe Bouvet, Patrick A. D. Grimont, Jean-Claude Desenclos, Helene Desqueyroux |
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| Rok vydání: | 1996 |
| Předmět: |
Serotype
Salmonella Veterinary medicine biology business.industry Incidence (epidemiology) Salmonella enteritidis General Engineering Outbreak General Medicine biology.organism_classification medicine.disease_cause fluids and secretions Salmonella enterica General Earth and Planetary Sciences Medicine Typing business Research Article General Environmental Science Phage typing |
| Zdroj: | BMJ. 312:91-94 |
| ISSN: | 1468-5833 0959-8138 |
| DOI: | 10.1136/bmj.312.7023.91 |
| Popis: | Objective: To assess the magnitude of a nationwide outbreak of infection with Salmonella enterica serotype paratyphi B and identify the vehicle and source of infection. Design: A case finding study of S paratyphi B infection between 15 August and 30 November 1993; a pair matched case-control study; an environmental investigation at a processing plant that produced a raw goats9 milk cheese incriminated in the outbreak; phage typing and genotyping of food and human S paratyphi B isolates. Setting: France, 15 August to 30 November 1993. Subjects: 273 patients with S paratyphi B infection; 59 pairs of cases and controls matched for age, sex, and city of residence. Main outcome measures: Numbers of cases and incidence rates by region of residence and age; matched odds ratios for dairy food preferences. Results: Among the 273 cases there was one death; 203 (78%) strains belonged to phage type 1 var 3. The incidence of infection was greatest in the region where goats9 milk cheese is commonly produced. Comparison of cases and controls showed a 12-fold greater risk of illness (95% confidence interval 1.6 to 92.3) from eating brand A unpasteurised goats9 milk cheese. S paratyphi B isolates of phage type 1 var 3 were recovered from cheese A, goats9 milk at the plant processing cheese A, and goats9 milk supplied to the plant by a single farm. Genotypic IS 200 typing of food and human 1 var 3 phage type isolates showed a common IS 200 pattern. Conclusion: This outbreak emphasises the potential health hazards of widely distributed unpasteurised milk products in France and the need for their close bacterial monitoring. Key messages Key messages Though the cheese was probably contaminated for more than two months, the outbreak continued undetected for a further two months The source of the infection was goats9 milk from one of the 40 farms that supplied the cheese processing plant Internal microbiological monitoring at the plant was not sensitive enough to detect the salmonella contamination initially Any batch of unpasteurised cheese or milk product should be closely monitored for Salmonella and should not be distributed until known to be clear |
| Databáze: | OpenAIRE |
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