SLC6A14, a Pivotal Actor on Cancer Stage: When Function Meets Structure

Autor:	Sara Adobati, Catriona M.H. Anderson, David T. Thwaites, Chiara Paravicini, Uliano Guerrini, Luca Palazzolo, T. Laurenzi, Ivano Eberini, Cesare Indiveri, S. Saporiti, Elisabetta Gianazza
Rok vydání:	2019
Předmět:	Protein Conformation alpha-Helical 0301 basic medicine Amino Acid Transport Systems Sodium Cell chemistry.chemical_element Molecular Dynamics Simulation Biochemistry Analytical Chemistry 03 medical and health sciences 0302 clinical medicine Neoplasms medicine Humans Amino acid transporter Amino Acids Neoplasm Staging chemistry.chemical_classification Binding Sites Dibasic acid Chemistry Cell Membrane Transporter Cell biology Amino acid Molecular Docking Simulation 030104 developmental biology Membrane medicine.anatomical_structure Molecular Medicine 030217 neurology & neurosurgery Function (biology) Biotechnology
Zdroj:	SLAS Discovery. 24:928-938
ISSN:	2472-5552
Popis:	SLC6A14 (ATB0,+) is a sodium- and chloride-dependent neutral and dibasic amino acid transporter that regulates the distribution of amino acids across cell membranes. The transporter is overexpresse...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91118156673a8dc28293643ee7d69dc5 https://doi.org/10.1177/2472555219867317 Zobrazit plný text záznamu