Is Infertility Associated with Childhood Autism?
| Autor: | Judith K. Grether, Mary S. Croughan, Loretta Camarano, Yinge Qian, Lisa A. Croen, Michael Schembri, Yvonne W. Wu |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Risk Infertility medicine.medical_specialty Databases Factual Ethnic group Gestational Age California Medical Records Childhood autism Pregnancy Pregnancy conception Developmental and Educational Psychology medicine Humans Autistic Disorder Child Psychiatry business.industry Public health Medical record Infant Newborn Infant Middle Aged medicine.disease Case-Control Studies Child Preschool Autism Female business Maternal Age Demography |
| Zdroj: | Journal of Autism and Developmental Disorders. 43:663-672 |
| ISSN: | 1573-3432 0162-3257 |
| DOI: | 10.1007/s10803-012-1598-5 |
| Popis: | Concerns persist about a possible link between infertility and risk of autism spectrum disorders (ASD). Interpretation of existing studies is limited by racial/ethnic homogeneity of study populations and other factors. Using a case-control design, we evaluated infertility history and treatment documented in medical records of members of Kaiser Permanente Northern California. Among singletons (349 cases, 1,847 controls), we found no evidence to support an increase in risk of ASD associated with infertility. Among multiple births (21 cases, 54 controls), we found an increased risk associated with infertility history and with infertility evaluations and treatment around the time of index pregnancy conception; however, small sample size and lack of detailed data on treatments preclude firm interpretation of results for multiple births. |
| Databáze: | OpenAIRE |
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