The Effect of Di (2-Ethylhexyl) Phthalate on Hair Trace Mineral Levels in Rats
| Autor: | Nurgül Günaydin, Emine Altin, Ali Ertekin, Neslihan Ormanci |
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| Rok vydání: | 2020 |
| Předmět: |
Gastric gavage
endocrine system Trace mineral Endocrinology Diabetes and Metabolism Clinical Biochemistry Phthalic Acids chemistry.chemical_element Zinc Manganese 010501 environmental sciences Body weight 01 natural sciences Biochemistry law.invention Inorganic Chemistry 03 medical and health sciences chemistry.chemical_compound Animal science law Animals Rats Wistar 0105 earth and related environmental sciences 0303 health sciences Chemistry 030302 biochemistry & molecular biology Biochemistry (medical) Phthalate General Medicine Rats Trace Elements Female Atomic absorption spectroscopy Corn oil Copper |
| Zdroj: | Biological trace element research. 200(2) |
| ISSN: | 1559-0720 |
| Popis: | We studied the effect of di (2-ethylhexyl) phthalate (DEHP) on rat hair deposition of Iron (Fe), Copper (Cu), Manganese (Mn), and Zinc (Zn). Four groups, each of eight of female Wistar rats weighing 250-300 g, were randomly distributed to (1) control (corn oil-based diet), (2) DEHP 20 (20 mg DEHP per kg body weight (bw), (3) DEHP 100 (100mg DEHP kg/bw, and (4) DEHP 500 (500 mg DEHP kg/bw). The diets were fed daily for 14 days by gastric gavage before the rats were sacrificed. Hair content of Fe, Cu, Mn, and Zn was analyzed with atomic absorption spectrophotometry. There were no significant effect of DEHP on hair Fe content. However, hair Cu, Mn, and Zn were increased after DEHP 20 exposure (p |
| Databáze: | OpenAIRE |
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