Brazilian Guidelines for transcranial doppler in children and adolescents with sickle cell disease
| Autor: | Maria Stella Figueiredo, Marcos Christiano Lange, Rodolfo D. Cançado, Robert J. Adams, Ana Claudia Mendonça dos Anjos, Marília A. Rugani, Andre Palma da Cunha Matta, Shirley Lopes de Castilho, Patrícia Moura, Joao Ricardo Friedrisch, Orlando Veloso, Viviane Flumignan Zétola, Ana Cristina Silva Pinto, Josefina Aparecida Pellegrini Braga, Ursula Thomé, Célia Maria Silva, Clarisse Lopes de Castro Lobo, Gisele Sampaio Silva, Sandra Fátima Menosi Gualandro, Paulo Ivo Cortez, Ana Claudia Celestino Bezerra Leite |
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| Přispěvatelé: | Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti, Faculdade de Ciências Médicas da Santa Casa de São Paulo, Fundação de Hematologia e Hemoterapia de Pernambuco, Universidade de São Paulo (USP), Fundação Hemocentro, Fundação Centro de Hematologia e Hemoterapia de Minas Gerais, UFRGS Hospital de Clínicas de Porto Alegre Serviço de Hematologia e Transplante de Medula Óssea, Universidade Federal de São Paulo (UNIFESP), Universidade Federal do Paraná Hospital de Clínicas Serviço de Neurologia, Ecodopler Laboratório, Universidade Federal do Rio de Janeiro Instituto de Puericultura e Pediatria Martagão Gesteira, Medical University of South Carolina |
| Rok vydání: | 2010 |
| Předmět: |
Hemoglobin
sickle Pediatrics medicine.medical_specialty Ultrasonography doppler transcranial/methods Adolescent MEDLINE Disease Guideline Special Article Therapeutic approach medicine Hemoglobin Child Stroke/prevention & control Stroke Sickle Hemoglobin lcsh:RC633-647.5 business.industry lcsh:Diseases of the blood and blood-forming organs Hematology Iron chelation therapy medicine.disease Anemia sickle cell Transcranial Doppler Hemoglobin/sickle Anemia sickle cell/diagnosis Ultrasonography doppler transcranial Anemia sickle cell/therapy business |
| Zdroj: | Revista Brasileira de Hematologia e Hemoterapia, Vol 33, Iss 1, Pp 43-48 (2011) Revista Brasileira de Hematologia e Hemoterapia Revista Brasileira de Hematologia e Hemoterapia v.33 n.1 2011 Revista brasileira de hematologia e hemoterapia Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular (ABHHTC) instacron:ABHHTC Repositório Institucional da UNIFESP Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP Revista Brasileira de Hematologia e Hemoterapia, Volume: 33, Issue: 1, Pages: 43-48, Published: FEB 2011 |
| ISSN: | 1516-8484 |
| Popis: | BACKGROUND: Sickle cell disease is the most common monogenic hereditary disease in Brazil. Although strokes are one of the main causes of morbidity and mortality in these patients, the use of transcranial Doppler to identify children at risk is not universally used. OBJECTIVE: To develop Brazilian guidelines for the use of transcranial Doppler in sickle cell disease children and adolescents, so that related health policies can be expanded, and thus contribute to reduce morbidity and mortality. METHODS: The guidelines were formulated in a consensus meeting of experts in transcranial Doppler and sickle cell disease. The issues discussed were previously formulated and scientific articles in databases (MEDLINE, SciELO and Cochrane) were carefully analyzed. The consensus for each question was obtained by a vote of experts on the specific theme. RESULTS: Recommendations were made, including indications for the use of transcranial Doppler according to the sickle cell disease genotype and patients age; the necessary conditions to perform the exam and its periodicity depending on exam results; the criteria for the indication of blood transfusions and iron chelation therapy; the indication of hydroxyurea; and the therapeutic approach in cases of conditional transcranial Doppler. CONCLUSION: The Brazilian guidelines on the use of transcranial doppler in sickle cell disease patients may reduce the risk of strokes, and thus reduce the morbidity and mortality and improve the quality of life of sickle cell disease patients. Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti Faculdade de Ciências Médicas da Santa Casa de São Paulo Fundação de Hematologia e Hemoterapia de Pernambuco Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto Hospital das Clínicas Fundação Hemocentro Fundação Centro de Hematologia e Hemoterapia de Minas Gerais UFRGS Hospital de Clínicas de Porto Alegre Serviço de Hematologia e Transplante de Medula Óssea Universidade Federal de São Paulo (UNIFESP) Universidade Federal do Paraná Hospital de Clínicas Serviço de Neurologia Ecodopler Laboratório Universidade Federal do Rio de Janeiro Instituto de Puericultura e Pediatria Martagão Gesteira Medical University of South Carolina Universidade de São Paulo Faculdade de Medicina Universidade Federal de São Paulo, EPM, São Paulo, Brazil SciELO |
| Databáze: | OpenAIRE |
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