Autor: |
Benjamin L, Ranard, Murad, Megjhani, Kalijah, Terilli, Hirad, Yarmohammadi, John, Ausiello, Soojin, Park |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Journal of Critical Care. 71:154114 |
ISSN: |
0883-9441 |
DOI: |
10.1016/j.jcrc.2022.154114 |
Popis: |
To examine the association between a measure of heart rate variability and sudden cardiac death (SCD) in COVID-19 patients.Patients with SARS-COV-2 infection admitted to Columbia University Irving Medical Center who died between 4/25/2020 and 7/14/2020 and had an autopsy were examined for root mean square of successive differences (RMSSD), organ weights, and evidence of SCD.Thirty COVID-19 patients were included and 12 had SCD. The RMSSD over 7 days without vs with SCD was median 0.0129 (IQR 0.0074-0.026) versus 0.0098 (IQR 0.0056-0.0197), p0.0001. The total adjusted adrenal weight of the non-SCD group was 0.40 g/kg (IQR 0.35-0.55) versus 0.25 g/kg (IQR 0.21-0.31) in the SCD group, p = 0.0007.Hospitalized patients with COVID-19 who experienced SCD had lower parasympathetic activity (RMSSD) and smaller sized adrenal glands. Further research is required to replicate these findings. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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