Recent advances in paper‐based preconcentrators by utilizing ion concentration polarization
| Autor: | Yuan Xichen, Ren Li, Shang Peng, Feng Huicheng, Meng Zhiyue, Yang Yang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Chip fabrication
Computer science Microfluidics 010401 analytical chemistry Clinical Biochemistry Nanotechnology 02 engineering and technology Ion concentration polarization Paper based Microfluidic Analytical Techniques 021001 nanoscience & nanotechnology 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry Polarization phenomenon High complexity 0210 nano-technology Polarization (electrochemistry) |
| Zdroj: | ELECTROPHORESIS. 42:1340-1351 |
| ISSN: | 1522-2683 0173-0835 |
| DOI: | 10.1002/elps.202000291 |
| Popis: | One of the most cited limitations of biochemical detection is its poor sensitivity, owing to the relatively high complexity of micro-samples. Moreover, some samples cannot be easily self-replicated and their abundance cannot be increased through traditional technologies. Therefore, the preconcentration of low-abundance samples is a key requirement for microfluidic biological analysis. In recent years, the ion-concentration polarization phenomenon has aroused widespread interest in the application of microfluidic technology. In addition, paper-based materials are readily available, easy to modify, and exhibit good hydrophilicity. The study of the ion-concentration polarization preconcentration of micro-samples in paper-based microfluidic chips is of considerable significance. In this review, we discuss the development and applications of ion-concentration polarization paper-based preconcentrator in the past 5 years, with emphasis on key progresses in chip fabrication and performance optimization under different conditions. The current needs and development prospects in this field have also been discussed. |
| Databáze: | OpenAIRE |
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