Effect of topical calcipotriol on congenital ichthyoses
| Autor: | M R van Dijk, Peter M. Steijlen, G.P.H. Lucker, P.C.M. van de Kerkhof |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Erythroderma Dermatology Administration Cutaneous Excipients chemistry.chemical_compound Calcitriol Double-Blind Method Psoriasis Congenital ichthyosis medicine Humans Prospective Studies Clinical efficacy Calcipotriol Skin business.industry Ichthyosis Middle Aged Lamellar ichthyosis medicine.disease chemistry Female Dermatologic Agents business |
| Zdroj: | British Journal of Dermatology. 131:546-550 |
| ISSN: | 1365-2133 0007-0963 |
| DOI: | 10.1111/j.1365-2133.1994.tb08558.x |
| Popis: | Summary We investigated the clinical efficacy of topically applied calcipotriol in six patients with congenital ichthyosis, using a double-blind, bilaterally paired, comparative approach. Unilateral improvement, in favour of the calcipotriol-treated side, was observed in three patients with lamellar ichthyosis. A beneficial response was also observed in a patient with bullous ichthyotic erythroderma of Brocq. No clinical side-effects or laboratory anomalies were observed. This study indicates that calcipotriol constitutes a new and promising approach in alleviating disorders of keratinization characterized by hyperproliferation, other than psoriasis. |
| Databáze: | OpenAIRE |
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