Impact of Prosthesis-Patient Mismatch on 1-Year Outcomes after Transcatheter Aortic Valve Implantation: Meta-analysis of 71,106 Patients
Autor: | Frederico Browne Correia de Araújo e Sá, Alexandre Motta de Menezes, Ricardo de Carvalho Lima, Álvaro M. Perazzo, Sérgio da Costa Rayol, Luiz Rafael P. Cavalcanti, Michel Pompeu Barros de Oliveira Sá, Roberto Diniz, Felipe Augusto Santos Sarargiotto |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
Prosthesis-Patient Mismatch
lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty Transcatheter aortic medicine.medical_treatment lcsh:Surgery MEDLINE 030204 cardiovascular system & hematology Prosthesis Risk Assessment Severity of Illness Index Transcatheter Aortic Valve Replacement 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Humans In patient Treatment Failure Aortic Stenosis business.industry Incidence (epidemiology) lcsh:RD1-811 General Medicine Odds ratio Confidence interval Prosthesis Failure lcsh:RC666-701 Meta-analysis Heart Valve Prosthesis Surgery Original Article Cardiology and Cardiovascular Medicine business Meta-Analysis |
Zdroj: | Brazilian Journal of Cardiovascular Surgery, Volume: 34, Issue: 3, Pages: 318-326, Published: 22 JUL 2019 Brazilian Journal of Cardiovascular Surgery v.34 n.3 2019 Brazilian Journal of Cardiovascular Surgery Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV) instacron:SBCCV Brazilian Journal of Cardiovascular Surgery, Vol 34, Iss 3, Pp 318-326 |
Popis: | Objectives: This study sought to evaluate the impact of prosthesis-patient mismatch (PPM) on the risk of early-term mortality after transcatheter aortic valve implantation (TAVI). Methods: Databases (Medical Literature Analysis and Retrieval System Online [MEDLINE], Excerpta Medica dataBASE [EMBASE], Cochrane Controlled Trials Register [CENTRAL/CCTR], ClinicalTrials.gov, Scientific Electronic Library Online [SciELO], Latin American and Caribbean Literature on Health Sciences [LILACS], and Google Scholar) were searched for studies published until February 2019. PPM after TAVI was defined as moderate if the indexed effective orifice area (iEOA) was between 0.85 cm2/m2 and 0.65 cm2/m2 and as severe if iEOA ≤ 0.65 cm2/m2. Results: The search yielded 1,092 studies for inclusion. Of these, 18 articles were analyzed, and their data extracted. The total number of patients included who underwent TAVI was 71,106. The incidence of PPM after TAVI was 36.3% (25,846 with PPM and 45,260 without PPM). One-year mortality was not increased in patients with any PPM (odds ratio [OR] 1.021, 95% confidence interval [CI] 0.979-1.065, P=0.338) neither in those with moderate PPM (OR 0.980, 95% CI 0.933-1.029, P=0.423). Severe PPM was separately associated with high risk (OR 1.109, 95% CI 1.041-1.181, P=0.001). Conclusion: The presence of severe PPM after TAVI increased early-term mortality. Although moderate PPM seemed harmless, the findings of this study cannot not rule out the possibility of it being detrimental, since there are other registries that did not address this issue yet. |
Databáze: | OpenAIRE |
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