Using the Berlin Questionnaire to Predict Obstructive Sleep Apnea in the General Population
| Autor: | Rob M. van Dam, Linda W.L. Tan, Adeline Tan, Jason Dean-Chen Yin, Chi-Hang Lee, Yan Yi Cheung |
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| Rok vydání: | 2016 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Population Primary care Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires medicine Humans education education.field_of_study Singapore Sleep Apnea Obstructive business.industry Reproducibility of Results Middle Aged medicine.disease Scientific Investigations respiratory tract diseases Obstructive sleep apnea 030228 respiratory system Neurology Physical therapy Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 13(3) |
| ISSN: | 1550-9397 |
| Popis: | The Berlin questionnaire is a self-administered questionnaire that was developed to identify subjects with obstructive sleep apnea (OSA) in primary care settings. This study evaluated the performance of the questionnaire to predict OSA in the general population.A sample of 242 subjects in a population-based cohort completed a home-based sleep study with an Embletta device (type 3 monitor). Subjects completed the Berlin questionnaire on the evening just prior to the sleep study. The sleep studies were manually scored according to the 2012 American Academy of Sleep Medicine (AASM) criteria.The prevalence of moderate-to-severe and severe OSA defined as apnea-hypopnea index (AHI) of ≥ 15 and ≥ 30 was 28.1% and 10.7%, respectively. Seventy-nine subjects (32.6%) were classified as high risk according to the Berlin questionnaire. The sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) of the questionnaire to predict an AHI ≥ 15 was 58.8%, 77.6%, 82.9%, and 50.6%, respectively. The area under the receiving operator characteristic (ROC) curve for moderate-to-severe OSA was 0.682. When used to predict an AHI ≥ 30, the sensitivity of the questionnaire increased to 76.9% with a small drop in specificity to 72.7%. The corresponding NPV, PPV, and area under the ROC curve of the questionnaire to predict severe OSA were 96.3%, 25.3%, and 0.748, respectively.The Berlin questionnaire may have utility in the general population setting as a screening tool for OSA in view of its good sensitivity and high NPV in ruling out severe OSA. |
| Databáze: | OpenAIRE |
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