Impact of a Rub and Rinse on Solution-Induced Corneal Staining
| Autor: | Lyndon Jones, Rachael C. Peterson, Desmond Fonn, Craig A. Woods |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
medicine.medical_specialty Corneal staining Adolescent genetic structures medicine.drug_class Biguanides Silicones law.invention Cornea Young Adult Double-Blind Method law Ophthalmology medicine Humans Therapeutic Irrigation Massage Staining and Labeling business.industry Biguanide Both lenses Hydrogels Middle Aged Contact Lenses Hydrophilic eye diseases Surgery Primary Prevention Lens (optics) Contact lens Contact Lens Solutions sense organs Sodium fluorescein business Disinfectants Optometry |
| Zdroj: | Optometry and Vision Science. 87:1030-1036 |
| ISSN: | 1040-5488 |
| DOI: | 10.1097/opx.0b013e3181ff9b6a |
| Popis: | To investigate whether the inclusion of a rub and rinse step before contact lens disinfection has an impact on solution-induced corneal staining.This was a prospective, double-masked, single investigator study. Twenty participants were recruited for two visits, where balafilcon-A lenses were worn bilaterally for 2 h. Each pair of lenses was prepared using two different methodologies. The "control" lens was transferred from the blister pack directly into a storage case containing polyhexamethylene biguanide-based lens care solution. The contralateral "test" lens was rubbed and simultaneously rinsed using the same polyhexamethylene biguanide-based care solution, for either 60 s (visit 1) or 20 s (visit 2). Both lenses were then soaked in the solution overnight. After baseline corneal staining assessments, the lenses were inserted following a randomized contralateral model. After 2 h, lenses were removed, corneal staining was regraded, and comfort scores were obtained.Rubbed and rinsed test lenses induced significantly less corneal staining than control lenses for all participants during visit 1 (mean ± SD: 516 ± 843 vs. 2170 ± 902; p0.001) and visit 2 (522 ± 417 vs. 2091 ± 965; p0.001). There was no significant difference between the test lenses during visits 1 and 2 (p = 0.72) or controls (p = 0.50). Comfort scores did not differ between eyes (p0.05).Corneal staining induced after 2 h of lens wear with the combination of balafilcon-A and polyhexamethylene biguanide-based lens care solution can be significantly reduced by including a rub and rinse step before overnight soaking. Further work is required to establish the longevity of this effect during the monthly wearing cycle. |
| Databáze: | OpenAIRE |
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